Clinical Trials

As an academic medical center, Our Lady of the Lake is committed to the advancement of healthcare through clinical innovation, medical education and scientific research.  We participate in a wide range of clinical trials that are used to determine whether new drugs or treatments are both safe and effective.

Be sure to consult with your physician before participating in a clinical trial.

Clinical Trials by Specialty

AUDIOLOGY
BLOOD DISORDERS
CANCER
DIABETES
GASTROENTEROLOGY
GENETIC DISEASES
INFECTIOUS DISEASES
NEUROLOGICAL
SURGICAL

AUDIOLOGY

Title:  Safety And Efficacy For The Eustachian Tube Balloon Catheter
Purpose:  The purpose of this research study is to test the use of a device to treat Eustachian Tube Dysfunction (ETD).
Principal Investigator:  Dr. Moisés A. Arriaga
Contact:  For more information, contact Ryan Landry, BSN, CCRN at (225) 765-2104.


BLOOD DISORDERS

Title:  Evaluation of Purified Poloxamer 188 in Children in Crisis (EPIC)
Purpose:  The purpose of this research study is to learn if MST-188 can decrease the amount of time children with sickle cell disease are in painful vaso-occlusive crisis.
Principal Investigator:  Dr. Vandy Black
Contact:  For more information, contact Ryan Landry, BSN, CCRN at (225) 765-2104.
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Title:  Study to Assess Safety and Impact of SelG1 With or Without Hydroxyurea Therapy in Sickle Cell Disease Patients with Sickle Cell-Related Pain Crises
Purpose:  The purpose of this study is to evaluate the safety and effectiveness of new medication SelG1 in the treatment of patients with sickle cell disease who experience sickle cell-related pain crises.
Principal Investigator:  Dr. Vandy Black
Contact:  For more information, contact Christine LeBoeuf, MSN, RN, OCN at (225) 765-5956.


CANCER

Title:  An Observational Study in Patients With HER2 Positive Metastatic Breast Cancer (SystHERs Registry)
Purpose:  The purpose of this study is to collect information on how patients who have metastic breast cancer are treated and how they respond to the various treatments.
Principal Investigator:  Dr. Patrick Stagg, II
Contact:  For more information, contact Christine LeBoeuf, MSN, RN, OCN at (225) 765-5956.
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Title:  A Study of the Bruton's Tyrosine Kinase Inhibitor, PCI-32765 (Ibrutinib), in Combination With Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone in Patients With Newly Diagnosed Non-Germinal Center B-Cell Subtype of Diffuse Large B-Cell Lymphoma
Purpose:  The purpose of this study is to compare the effects of ibrutinib when given in combination with rituximab, cyclohosphamide, doxorubicin, vincristine and prednisone (R-CHOP) versus RCHOP and placebo.
Principal Investigator:  Dr. Vince Calaldo
Contact:  For more information, contact Christine LeBoeuf, MSN, RN, OCN at (225) 765-5956.
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Title:  Connect® MDS and AML: The Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML) Disease Registry
Purpose:  The purpose of this study is to better understand patterns related to diagnosis, treatment and outcomes for patients, and to better understand the effect different treatments have on a patient’s disease and their quality of life.
Principal Investigator:  Dr. Vince Calaldo
Contact:  For more information, contact Christine LeBoeuf, MSN, RN, OCN at (225) 765-5956.
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Title: A Randomized, Phase 2 Study to Assess the Safety and Efficacy of CRLX101 in Combination with Bevacizumab in Patients with Metastatic Renal Cell Carcinoma (RCC) versus the Standard of Care
Purpose: The purpose of this research study is to determine how well CRLX101 (study drug) in combination with Avastin works in treating  renal cell cancer that stops responding to treatment.
Principal Investigator:  Dr. Vince Calaldo
Contact:  For more information, contact Christine LeBoeuf, MSN, RN, OCN at (225) 765-5956.

DIABETES

Title:  Natural History of the Development of Type 1 Diabetes
Purpose:  The purpose of this study is to learn more about how Type 1 Diabetes occurs.
Principal Investigator:  Dr. James Garner
Contact:  For more information, contact Christine LeBoeuf, MSN, RN, OCN at (225) 765-5956.


GASTROENTEROLOGY

There are no Gastroenterology studies open at this time.

GENETIC DISEASES

There are no Gastroenterology studies open at this time.

INFECTIOUS DISEASES

Coming Soon:
Title:  A Phase 1, Non-Comparative, Open-Label Study to Characterize the Pharmacokinetics of a Single Intravenous Dose of Ceftolozane/Tazobactam in Pediatric Patients Receiving Standard of Care Antibiotic Therapy for Proven or Suspected Gram-Negative Infection or for Peri-Operative Prophylaxis
Purpose:  The purpose of this research study is to determine how the body handles a single intravenous dose of ceftolozane/tazobactam in patients ranging in age from seven days after birth up to 18 years old.
Principal Investigator:  Dr. Micheal Bolton
Contact:  For more information, contact Christine LeBoeuf, MSN, RN, OCN at (225) 765-5956.
The study is not yet listed on clinical trials.gov.


NEUROLOGICAL

Title:  A Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation Study of NNZ-2566 in Patients with Traumatic Brain Injury (Intrepid2566)
Purpose:  The purpose of this study is to assess the safety of a new investigational drug, NNZ-2566, in human subjects with traumatic brain injury.
Principal Investigator:  Dr. Tomas Jacome
Contact:  For more information, contact Ryan Landry, BSN, CCRN at (225) 765-2104.

SURGICAL

Title:  Freedom Inguinal Hernia Repair
Purpose:  The purpose of this study is to determine how the Insightra Freedom Hernia Device impacts quality of life for patients.
Principal Investigator:  Dr. Karl LeBlanc
Contact:  For more information, contact Ryan Landry, BSN, CCRN at (225) 765-2104.
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Title:  Reversal of the Anticoagulant Effects of Dabigatran by Intravenous Administration of 5.0g Idarucizumab (BI 655075) in Patients Treated Wtih Dabigatran Etexilate Who Have Uncontrolled Bleeding or Require Emergency Surgery or Procedures
Purpose:  The purpose of this study is to reverse the anticoagulent effects of Dabigatran in patients who have overt bleeding, or who require emergency surgery or invasive procedures.
Principal Investigator:  Dr. Michael Fahr
Contact:  For more information, contact Ryan Landry, BSN, CCRN at (225) 765-2104.

As an academic medical center, Our Lady of the Lake is committed to the advancement of healthcare through clinical innovation, medical education and scientific research.  We participate in a wide range of clinical trials that are used to determine whether new drugs or treatments are both safe and effective.