Myocardial biopsy is done during cardiac catheterization or similar procedure.
The procedure will take place in a hospital radiology department, special procedures room, or cardiac diagnostics laboratory. You may be given a sedative prior to the procedure to help you relax, but you will remain awake and able to follow instructions during the test. You will lie flat on a stretcher or table while the test is being done.
The skin is scrubbed and a local numbing medicine (anesthetic) is given.
A surgical cut will be made your arm, neck, or groin. The health care provider inserts a thin tube (catheter) through a vein or artery, depending on whether tissue will be taken from the right or left side of the heart.
If the biopsy is done without another procedure, the catheter is usually placed through a vein in the neck and then carefully threaded into the heart. The doctor uses moving x-ray images (fluoroscopy) to guide the catheter to the correct area. Once in position, a special device with jaws on the tip is used to remove small pieces of tissue from the heart muscle.
The procedure may last 1 or more hours.