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Gallbladder radionuclide scan

Gallbladder radionuclide scan


Radionuclide - gallbladder; Gallbladder scan; Biliary scan; Cholescintigraphy

Gallbladder radionuclide scan is a test that uses radioactive material to check gallbladder function. It is also used to look for bile duct blockage.

I Would Like to Learn About:

  • How the Test is Performed

    The health care provider will inject a radioactive chemical called a gamma emitting tracer into a vein. This material collects mostly in the liver. It will then flow with bile into the gallbladder.

    For the test:

    • You lie face up on a table under a scanner called a gamma camera. The scanner detects the rays being emitted from the tracer. A computer displays images of where the tracer is found in the organs.
    • Images will be taken every 5 to 15 minutes. Most of the time, the test takes about 1 hour, but it can take up to four hours.

    If the doctor cannot see the gallbladder after certain amount of time, you may be given a small amount of morphine. This can help the radionuclide get into the gallbladder. The morphine may cause you to feel tired after the exam.

    In some cases, the doctor may give you a medicine during this test to see how well your gallbladder squeezes (contracts).

  • How to Prepare for the Test

    You need to eat something within a day of the test. However, you must stop eating or drinking 4 hours before the test starts.

  • How the Test will Feel

    You will feel a sharp prick from the needle when the tracer is injected into the vein. The site may be sore after the injection. There is normally no pain during the scan.

  • Why the Test is Performed

    This test is very good for detecting a sudden infection of the gallbladder or blockage of a bile duct. It is also helpful in determining whether there is rejection of a transplanted liver.

    The test can also be used to detect long-term gallbladder problems.

  • What Abnormal Results Mean

    • Abnormal anatomy of the bile system (biliary anomalies)
    • Bile duct obstruction
    • Bile leaks or abnormal ducts (resulting from cysts)
    • Cancer of the hepatobiliary system
    • Gallbladder infection (cholecystitis)
    • Gallstones
    • Infection of the gallbladder, ducts, or liver
    • Liver disease
    • Transplant rejection (after liver transplant)
  • Risks

    There is a small risk to pregnant or nursing mothers. Unless it is absolutely necessary, the scan will be delayed until you are no longer pregnant or nursing.

    The amount of radiation is small (less than that of a regular x-ray). It is almost all gone from the body within 1 or 2 days. Your risk from radiation may increase if you have a lot of scans.

  • Considerations

    Most of the time, this test is done only if a person has sudden pain that the doctor thinks may be from gallbladder disease or gallstones. For this reason, some people may need urgent treatment based on the test results.

    This test is combined with other imaging (such as CT or ultrasound). After the gallbladder scan, the patient may be prepared for surgery, if needed.

Related Information

  BileAcuteAcute cholecystiti...GallstonesBile duct obstruct...CystTransplant rejecti...Liver transplant...Liver diseaseLiver cancer - Hep...     Gallstones and gal...


Afdahl NH. Diseases of the gall bladder and bile ducts In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine. 24th ed. Philadelphia, PA: Saunders Elsevier; 2011:chap 158.

Wang DQH, Afdahl NH. Gallstone disease. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 9th ed. Philadelphia, PA: Saunders Elsevier; 2010:chap 65.


Review Date: 1/13/2013  

Reviewed By: Jason Levy, MD, Northside Radiology Associates, Atlanta, GA. Also reviewed by A.D.A.M. Health Solutions, Ebix, Inc., Editorial Team: David Zieve, MD, MHA, Bethanne Black, Stephanie Slon, and Nissi Wang.

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