Foot, leg, and ankle swelling is common with the following situations:
Injury or surgery involving the leg, ankle, or foot can cause swelling. Swelling may also occur after pelvic surgery, especially for cancer.
Long airplane flights or car rides, as well as standing for long periods of time, often lead to some swelling in the feet and ankles.
Swelling may occur in women who take estrogen or during parts of the menstrual cycle. Most women have some swelling during pregnancy. More severe swelling during pregnancy may be a sign of preeclampsia (also called toxemia), a serious condition that includes high blood pressure and swelling.
Swollen legs may be a sign of heart failure, kidney failure, or liver failure. In these conditions, there is too much fluid in the body.
Certain medications may also cause your legs to swell:
- Antidepressants, including MAO inhibitors (such as phenelzine and tranylcypromine) and tricyclics (such as nortriptyline, desipramine, and amitriptyline)
- Blood pressure medicines, called calcium channel blockers (such as nifedipine, amlodipine, isradipine, nicardipine, felodipine, diltiazem, and verapamil)
- Hormones, such as estrogen (in birth control pills or hormone replacement therapy) and testosterone